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Massumeh Noushin Seyhoun was an Iranian painter, curator, and gallerist, and the founder of Seyhoun Gallery in Tehran, the longest-lived art gallery in Iran.

Born in 1934 in Rasht, Massumeh Seyhoun was originally named Monir Noushin. Her family later settled in Ahvaz, and she changed her name to Massumeh. She studied at the Faculty of Fine Arts in Tehran under the guidance of Hooshang Seyhoun, an architect, sculptor, and painter, who eventually became her husband. Together, they had two children, a son named Nader and a daughter named Maryam.

In the mid-1990s, when Seyhoun's health began to decline, she handed control of the gallery to her son Nader. Her daughter Maryam opened Seyhoun Gallery in Los Angeles, on Melrose Avenue in West Hollywood, serving as an American outpost of the Tehran gallery. This gallery exhibits works by Iranian expatriate artists, as well as artists based in Iran, many of whom have collaborated with Seyhoun Gallery in Tehran.